Toshiba's Portege Z10t detachable Ultrabook debuts at IDF (hands-on)

Right after Intel's somewhat mundane announcement of the Ultrabook Convertible and Ultrabook Detachable sub-brands at IDF in Beijing, SVP Kirk Skaugen surprised us by whipping out an unnamed laptop coming from Toshiba, so we jumped onto the stage to get a sniff of the only two units at the venue. Judging by the looks of it, we're confident that this is actually the Portege Z10t that hit the FCC last month -- the vents, camera and logo on the back match those in the drawing (embedded after the break) filed in the application.

Gallery: Toshiba Portege Z10t ???

Filed under: Laptops, Tablets

Comments

Source: http://www.engadget.com/2013/04/10/toshiba-portege-z10t-idf/

troy miracle joel osteen annette funicello luke bryan margaret thatcher

High lead levels in US rice imports

10 April 2013 Last updated at 19:23 ET By Jason Palmer BBC science reporter, New Orleans

Analysis of commercially available rice imported into the US has revealed it contains levels of lead far higher than regulations suggest are safe.

Some samples exceeded the "provisional total tolerable intake" (PTTI) set by the US Food and Drug Administration (FDA) by a factor of 120.

The report at the American Chemical Society Meeting adds to the already well-known issue of arsenic in rice.

The FDA told the BBC it would review the research.

Lead is known to be harmful to many organs and the central nervous system.

It is a particular risk for young children, who suffer significant developmental problems if exposed to elevated lead levels.

Because rice is grown in heavily irrigated conditions, it is more susceptible than other staple crops to environmental pollutants in irrigation water.

Recent studies have highlighted the presence of arsenic in rice - prompting consumption advice from the UK's Food Standards Agency and more recently from the FDA.

However, other heavy metals represent a risk as well.

Dr Tsanangurayi Tongesayi of Monmouth University in New Jersey, US, and his team have tested a number of imported brands of rice bought from local shops.

The US imports about 7% of its rice, and the team sampled packaged rice from Bhutan, Italy, China, Taiwan, India, Israel, the Czech Republic and Thailand - which accounts for 65% of US imports.

The team measured the lead levels in each country-category and calculated the lead intake on the basis of daily consumption. The results will be published in the Journal of Environmental Science and Health (Part B).

"When we compared them, we realised that the daily exposure levels are much higher than those PTTIs," said Dr Tongesayi.

"According to the FDA, they have to be more than 10 times the PTTI levels (to cause a health concern), and our values were two to 12 times higher than those 10 times," he told BBC News.

'Globalised market'

"So we can only conclude that they can potentially cause harmful effects."

That factor of 120 (12 times higher than 10 times the PTTI) alluded to by Dr Tongesayi is for Asian children, who are most susceptible by virtue of age and comparatively high rice intake on average.

For non-Asian adults the excesses above the PTTI ranged from 20 to 40.

Rice from China and Taiwan had the highest lead levels, but Dr Tongesayi stressed that all of the samples significantly exceeded the PTTIs.

Dr Tongesayi has also worked on quantifying arsenic contamination - and is in effect working his way through the heavy metals one by one to determine their prevalence.

The problem, he said, is the range of agricultural practices around the world.

"If you look through the scientific literature, especially on India and China, they irrigate their crops with raw sewage effluent and untreated industrial effluent," he explained.

"Research has been done in those countries, and concerns have been raised because of those practices, but it's still ongoing."

Dr Tongesayi also said that the increasing practice of sending electronic waste to developing countries - and the pollution it leads to - exacerbates the problem.

"With a globalised food market, we eat food from every corner of the world, but pollution conditions are? different from region to region, agricultural practices are different from region to region, but we ignore that.

"Maybe we need international regulations that will govern production and distribution of food."

So far, such international oversight exists informally in the form of the Codex Alimentarius, a collection of food-safety standards first set out by the United Nations.

FDA spokesman Noah Bartolucci told BBC News that the "FDA plans to review the new research on lead levels in imported rice released today".

"As part of an ongoing and proactive effort to monitor and address contaminants in food traded internationally, FDA chairs an international working group to review current international standards for lead in selected commodities, including rice, and to revise, if necessary, maximum lead levels under the? Codex Alimentarius," he said.

Source: http://www.bbc.co.uk/news/science-environment-22099990#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

james jones aladdin black forest ufc 144 fight card ufc 144 results acura nsx all star weekend 2012

Signature of circulating breast tumor cells that spread to the brain found

Apr. 10, 2013 ? Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor College of Medicine in a report that appears online in the journal Science Translational Medicine.

"What prompted us to initiate this study was our desire to understand the characteristics of these cells," said Dr. Dario Marchetti, professor of pathology at BCM, director of the CTC (circulating tumor cell) Core Facility at BCM and a member of the NCI-designated Dan L. Duncan Cancer Center at BCM. Often, he said, circulating tumor cells (CTCs) from breast cancer patients which spread or metastasize to the brain are not identified by the current method for identifying such cells approved by the U.S. Food and Drug Administration (CellSearch? platform).

While this system is based on the detection of antibodies that target the epithelial cell adhesion molecule (EpCAM), the biomarkers identified by Marchetti and his colleagues include human epidermal growth factor receptor 2 (HER2+), epidermal growth factor receptor (EGFR), heparanase (HPSE) and Notch1 -- and not EpCAM . Together, said Marchetti, these four proteins, previously known to be associated with cancer metastasis, spell out the signature of circulating tumors cells that travel to the brain.

Marchetti, using sophisticated techniques to test samples provided by Dr. Morris D. Grove of The University of Texas MD Anderson Cancer Center, also found this same pattern of proteins in the tissue taken from brain metastases of animals injected with breast cancer circulating tumor cells (CTCs).

They tested these special circulating tumor cells in laboratory models and found that they are highly invasive and capable of spread in live animals. They also found cells with this signature in the metastatic tumors of animals with breast cancer.

"We were able to grow these cells in vitro (in the laboratory in culture) for the first time ever," said Marchetti.

Circulating tumor cells are a promising method of identifying and monitoring solid tumors and could replace tumor biopsies in some cases. However, the promise is still being studied by experts such as Marchetti. In this case, he has identified a new signature for such cells -- one that directs their activities toward spreading cancer to brain -- an outcome with frequently fatal consequences.

The study not only identifies a novel signature of circulating tumor cells, it shows the limitations of currently approved platforms used to identify cancer in this way. Understanding such cells can help scientist understand how the disease spreads -- an initial step in developing new methods of treating metastatic disease.

"We don't claim that these biomarkers are the only important ones," said Marchetti. "We hope to find novel markers in brain metastasis that will make diagnosis and monitoring even more targeted."

They are also trying to find ways to link these circulating tumor cells back to the signature of the original or primary tumor.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

---

Story Source:

The above story is reprinted from materials provided by Baylor College of Medicine, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. L. Zhang, L. D. Ridgway, M. D. Wetzel, J. Ngo, W. Yin, D. Kumar, J. C. Goodman, M. D. Groves, D. Marchetti. The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis. Science Translational Medicine, 2013; 5 (180): 180ra48 DOI: 10.1126/scitranslmed.3005109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/VnxBuNVEgqk/130410141528.htm

Election Results Map Early voting results BBC Dick Morris Daily Show provisional ballot npr

Markets steady as US earnings season begins

LONDON (AP) ? A mixed earnings report from aluminum company Alcoa Corp. failed to provide markets with much direction Tuesday as concerns over North Korea, bird flu in China and Europe's debt crisis kept many investors on the sidelines.

Alcoa, as usual, kicked off the reporting season in an after-hours statement Monday with first-quarter earnings of 11 cents a share, well ahead of expectations of 8 cents. However, much of the impact in markets was negated by the news that revenues fell.

"The first company to unveil its update in a reporting season can often set the tone," said David Madden, market analyst at IG.

In Europe, the FTSE 100 index of leading British shares rose 0.6 percent to close at 6,313.21 while Germany's DAX fell 0.3 percent to 7,637.51. The CAC-40 in France rose 0.1 percent to 3,670.72.

In the U.S., the Dow Jones industrial average was up 0.2 percent at 14,634 71 while the broader S&P 500 index rose 0.1 percent to 1,564.71.

Much of the focus in markets will remain on the U.S. corporate sector over the coming weeks as investors seek to assess the health of the world's largest economy. The flow of earnings picks up through the week with banks Wells Fargo and JPMorgan Chase due to report on Friday.

"Traders can sometimes appear a little over-reliant on the first number, setting the market up for a fall should the next readings serve to disappoint," said Mike McCudden, head of derivatives at stockbroker Interactive Investor.

Another key focus will be Japanese markets.

The Nikkei 225 stock index in Tokyo has posted strong gains over the past week as the Bank of Japan unveiled an aggressive new approach to shake the world's third-largest economy out of its near-two-decade stagnation and growth-crippling deflation. The bank will pump huge amounts of money into the economy via government bond purchases and pursue a 2 percent inflation target in order to spark lending and spending.

Earlier, the rally ran out of stream and the Nikkei edged down slightly to close at 13,192.35. However, the yen continues to push four-year lows against the dollar, and was trading 0.4 percent lower at 98.94 yen. It hasn't breached 100 yen since April 2009.

Gains in Hong Kong and mainland China markets reflected a decreasing sense of alarm over the outbreak of a new bird flu strain in eastern China that has killed seven people so far. There is no sign that the virus is being transmitted from human to human.

Hong Kong's Hang Seng rose 0.7 percent to 21,870.34 and the Shanghai Composite Index added 0.6 percent to 2,225.77. The smaller Shenzhen Composite Index advanced 0.8 percent to 926.22.

Another focus in Asia has been the rise in tensions between the two Koreas, as Pyongyang recalled all its workers from the Kaesong industrial complex, the last major economic link between South Korea and North Korea. South Korea's Kospi rose 0.1 percent to 1,920.74 but the country's currency, the won, hovered at its lowest levels since July 2012.

Trading elsewhere was fairly lackluster, with the euro 0.4 percent higher on the day at $1.3089 and the benchmark New York oil rate up 19 cents at $93.55 a barrel.

____

Pamela Sampson in Bangkok contributed to this report.

Source: http://news.yahoo.com/markets-steady-us-earnings-season-begins-160212985--finance.html

al sharpton actuary elon musk fox mole manson bubba watson recent earthquakes

Video: Herbalife Halted For News Pending

Sorry, Readability was unable to parse this page for content.

Source: http://www.nbcnews.com/video/cnbc/51479057/

Eddie Murphy died Suzanne Barr Clint Eastwood speech Maria Montessori clint eastwood Julian Castro Blue Moon August 2012

Serbia rejects EU-brokered Kosovo deal

BELGRADE, Serbia (AP) ? Serbia rejected on Monday a European Union-brokered deal for reconciliation with its former province of Kosovo ? a defiant move that could jeopardize the Balkan country's EU membership aspirations and fuel tensions in the region.

The EU had given Serbia until Tuesday to say whether it would relinquish its effective control over northern Kosovo in exchange for the start of Serbia's EU membership negotiations.

Even before the government rejection, Deputy Prime Minister Aleksandar Vucic ? Serbia's most powerful governing party leader who also serves as the defense minister ? said the plan is unacceptable because it does not give more autonomy to minority ethnic Serbs in Kosovo who together with Serbia reject Kosovo's 2008 declaration of independence.

"The Serbian government cannot accept the proposed principles ... because they do not guarantee full security, survival and protection of human rights for the Serbs in Kosovo," Prime Minister Ivica Dacic said. "Such an agreement could not be implemented and would not lead to a lasting and sustainable solution."

Catherine Ashton, the EU's foreign policy chief, said after the eighth round of talks between Serbian and Kosovo officials last week in Brussels that she wanted a response from both sides and that the bloc's mediation was over.

Despite warnings that there will be no more EU-sponsored mediation, Vucic and the government called for more talks with the rival ethnic Albanians leaders of Kosovo.

"If there is a negative answer from (the EU), that would be bad news for Serbia, Kosovo and the EU," Vucic said. "If that happens, we would have to start thinking of what to do next.

"We don't want Serbia isolated from the world, but we have to protect our interests. It is highly important that we reach an agreement."

In a statement issued after Serbia's rejection, Ashton called on Belgrade "to make a last effort to reach an agreement, for the benefit of their people." But while she made no mention of formally extending the negotiation process, she said she hoped to lead "the discussion in the EU over the next few days in support of a real step forward by both Serbia and Kosovo towards their European future."

The rejection of the proposal could severely hamper Serbia's EU membership aspirations ? which would include millions of dollars of promised accession funds. The rejection also could lead to more tensions in the Balkans, which is still reeling from the bloody wars of the 1990s when Serbia tried to prevent the breakup of the former Yugoslav federation by force.

While some 90 countries ? including the United States and most EU nations ? have recognized Kosovo's 2008 declaration of independence, it has been rejected by Serbia and ally Russia.

The most contentious issue in the talks was the status of northern Kosovo, where ethnic Serbs dominate the population and refuse to accept the authority of the ethnic Albanian-controlled government in Kosovo's capital, Pristina.

Germany has made giving up control of Kosovo's north the key condition for the start of Serbia's EU accession negotiations.

The stumbling block in the talks was a Serbian demand that ethnic Serbs, who represent about 10 percent of Kosovo's 2 million people, have their own judiciary and police force. But Kosovo officials have rejected that, saying it would be tantamount to a division of Kosovo into two separate entities.

In Serbia, there are increasing calls among nationalists that Serbia should turn to its ally Russia instead of becoming an EU member. There also are suggestions from hardliners that Serbia should use force to reoccupy Kosovo, which it surrendered after a three-month NATO bombing campaign that pushed out its troops in 1999.

Vucic, a former ultranationalist turned moderate, said a military solution is out of the question.

"I'm hearing some 'heroes' who were never brave who are giving us lessons on how we should stroll into Pristina," he said. "They should not tell us what our decisions should be."

Several hundred far-right supporters demonstrated in front of the government headquarters in Belgrade during the Cabinet session, demanding that no deal is signed with the EU and Kosovo's leaders.

___

Associated Press writer Jovana Gec contributed to this report.

Source: http://news.yahoo.com/serbia-rejects-eu-brokered-kosovo-deal-155216716.html

the hartford illinois primary 2012 michael bay zsa zsa gabor illinois primary trayvon martin 911 call kiribati

You Can Make Insane Weapons Out of Airport Duty-Free Items

It's widely acknowledged that the purpose of airport security isn't to protect passengers from harm—it's to try and stop major in-flight attacks which take down the plane. That doesn't stop airports imposing plenty of silly security rules—but a report in Dutch newspaper Nu reveals just how easy it is to create dangerous tools from airport duty-free stores regardless. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/_PLQVGHUQ6A/making-weapons-from-airport-duty+free-stores

usps Dick Van Dyke pro bowl victoria azarenka Royal Rumble 2013 senior bowl norovirus